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Fortune 500: Titans and Disruptors of Industry

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Hosted by Fortune Editor-in-Chief Alyson Shontell, Fortune 500: Titans and Disruptors of Industry goes in-depth with the powerful thought leaders shaping both the world of business and the very way we live. Subscribe to the show on Spotify or Apple Podcasts.
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Fortune 500: Titans and Disruptors of Industry
Hosted by Fortune Editor-in-Chief, Alyson Shontell, Fortune 500: Titans and Disruptors of Industry goes in depth with the powerful thought leaders shaping both the world of business and the very way we live.
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How Bill Ackman Built Success on Cold-Calling BillionairesAugust 5, 2026
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FedEx CEO on How AI Can Fix a $1.8 Trillion Global Supply Chain ProblemJuly 15, 2026
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$4 Trillion Savings Gap: TIAA's CEO on The Retirement CrisisJune 17, 2026
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Qualcomm's AI takeover | Titans and DisruptorsMay 6, 2026
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Delta: Bankrupt to Billions | Titans and DisruptorsApril 1, 2026
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The end of work: Vinod Khosla's bold AI prediction | Titans and DisruptorsMarch 4, 2026
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Google's AI boss made OpenAI issue code red. Now he wants to solve disease. | Titans and DisruptorsFebruary 11, 2026
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Pfizer CEO took on COVID. Now he wants to cure cancer | Titans and DisruptorsJanuary 27, 2026
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Kamala Harris says the 'Glass Cliff' Suggests Finality: "I'm Not Into That"October 15, 2025
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Jamie Dimon on What Kills Companies and the Key to Business LeadershipOctober 15, 2025
Vinod Khosla, wearing a black suit jacket, looks forward.
AI
OpenAI investor Vinod Khosla predicts today’s 5-year-olds won’t ever need to get jobs thanks to AI
By Sasha RogelbergMarch 4, 2026
Demis Hassabis, chief executive officer of Google DeepMind
Success
The CEO of Google DeepMind juggles another job as the founder of a multibillion-dollar startup by starting a second workday at 10 p.m.
By Emma BurleighFebruary 12, 2026
Deepmind CEO
AI
Google Gemini boss describes working with founders Larry Page and Sergey Brin to win the AI future
By Nick LichtenbergFebruary 12, 2026
Demis Hassabis
AI
Google’s Nobel-winning AI leader sees a ‘renaissance’ ahead—after a 10- or 15-year shakeout
By Nick LichtenbergFebruary 11, 2026
How Demis Hassabis is leading Google through an innovator’s dilemma—and made OpenAI declare ‘code red’
C-Suite
How Demis Hassabis is leading Google through an innovator’s dilemma—and made OpenAI declare ‘code red’
By Fortune EditorsFebruary 11, 2026
Albert Bourla
Success
Pfizer CEO Albert Bourla’s best leadership advice: Being optimistic is better than being right
By Preston ForeJanuary 31, 2026
‘We’ll save the world from cancer’: Inside Pfizer CEO’s $23 billion post‑COVID bet on oncology
C-Suite
‘We’ll save the world from cancer’: Inside Pfizer CEO’s $23 billion post‑COVID bet on oncology
By Nick LichtenbergJanuary 30, 2026
Pfizer CEO says he used ‘emotional blackmail’ to get employees to achieve impossible goals during COVID-19
C-Suite
Pfizer CEO says he used ‘emotional blackmail’ to get employees to achieve impossible goals during COVID-19
By Eva RoytburgJanuary 29, 2026
Graphic reads: Fortune Titans and Disruptors of Industry with Albert Bourla, CEO of Pfizer, Hosted by Alyson Shontell (both pictured).
C-Suite
Pfizer CEO on how he struck a deal with President Trump in 10 days to lower American drug costs
By Fortune EditorsJanuary 27, 2026
Jamie Dimon’s worldview: JPMorgan Chase CEO on the economy, an AI bubble, and leadership
C-Suite
Jamie Dimon’s worldview: JPMorgan Chase CEO on the economy, an AI bubble, and leadership
By Fortune EditorsOctober 17, 2025
Former Vice President Kamala Harris: ‘I’m not into’ finality
Politics
Former Vice President Kamala Harris: ‘I’m not into’ finality
By Fortune EditorsOctober 15, 2025
Ramp founder Eric Glyman: How I built a $22.5 billion startup in 2,367 days
Big Tech
Ramp founder Eric Glyman: How I built a $22.5 billion startup in 2,367 days
By Fortune EditorsSeptember 19, 2025
Accenture CEO weighs in on why so many AI projects have failed with 3 red flags to watch out for
Success
Accenture CEO weighs in on why so many AI projects have failed with 3 red flags to watch out for
By Marco Quiroz-GutierrezAugust 31, 2025
Accenture CEO Julie Sweet says Fortune 500s can survive AI—but they have to be willing to reinvent themselves top to bottom
Leadership
Accenture CEO Julie Sweet says Fortune 500s can survive AI—but they have to be willing to reinvent themselves top to bottom
By Fortune EditorsAugust 30, 2025
Accenture CEO Julie Sweet says there’s one thing you should never do if you get offered a big job you don’t feel ready for
Success
Accenture CEO Julie Sweet says there’s one thing you should never do if you get offered a big job you don’t feel ready for
By Preston ForeAugust 28, 2025
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Success
Billionaire Joshua Kushner just bought the Lakers for $12.5 billion—OpenAI's Sam Altman once said he 'doesn't care' what others thinkplaceholder alt text
By Orianna Rosa RoyleAugust 14, 2026
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Billionaire Home Depot cofounder Bernie Marcus' foundation donates nearly $30 million toward stem cell research for heart attacksplaceholder alt text
By Sydney LakeAugust 14, 2026
Cybersecurity
People are going to extreme lengths to stop themselves from being filmed through Meta’s ‘pervert glasses’placeholder alt text
By Joshua HongAugust 14, 2026
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