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F500-2021-305-Boston Scientific

Incorporated in 1979, Boston Scientific develops and manufactures medical devices for customers in the U.S. and various international markets and emerging markets. The slowdown in elective surgeries in 2020, due to the pandemic, hurt Boston Scientific's business: Revenue sank 8% to $9.9 billion and the company lost $82 million. In the first quarter of 2021, however, the company reported sales growth in each of its reportable segments and an 8% year-over-year increase in net sales.

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F500-2020-296-Boston-Scientific

Boston Scientific makes medical devices such as pacemakers and stents for a number of health conditions.

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Wal-Mart stayed on top as its sales crept closer to half-a-trillion dollars. Apple moved into the top five. And UnitedHealth Group continued its steady climb. 

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Boston Scientific Corporation is a medical technology company that develops minimally invasive therapies and devices to address heart failure and rhythm disorders, gastrointestinal problems, and chronic pain. The company is known for its Watchman implant, designed to reduce the risk of stroke and heart attack in people with atrial fibrillation and to reduce their reliance on blood thinners.

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Q4 2024

Boston Scientific (BSX): Company Profile, Stock Price, News, Rankings

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Boston Scientific

boston scientific

Good morning, and welcome to the Boston Scientific Fourth Quarter twenty twenty four Earnings Call. All participants will be in listen only mode. Please note this event is being recorded. I would now like to turn the conference over to John Monson, Senior Vice President, Investor Relations. Please go ahead.

Thank you, Drew, and thanks everyone for joining us. With me today are Mike Mahoney, Chairman and Chief Executive Officer and Dan Brennan, Executive Vice President and Chief Financial Officer. During the Q and A session, Mike and Dan will be joined by our Chief Medical Officer, Doctor. Ken Stein. We issued a press release earlier this morning announcing our Q4 and full year twenty twenty four results, which included reconciliations of the non GAAP measures used in this release.

The release, as well as reconciliations of the non GAAP measures used in today's call, can be found on the Investor Relations section of our website. Please note that on the call, operational revenue excludes the impact of foreign currency fluctuations and organic revenue further excludes acquisitions and divestitures for which there are less than a full period of comparable net sales. Guidance excludes the previously announced agreements to acquire BOLT Medical and Entera Oncology, which are expected to close in the first half of twenty twenty five subject to customary closing conditions. For more information, please refer to the Q4 Financial and Operational Highlights deck, which may be found on the Investor Relations section of our website. On this call, all references to sales and revenue are organic and relative growth is compared to the same quarter of the prior year unless otherwise specified.

This call contains forward looking statements regarding, among other things, our financial performance, business plans, and product performance and development. These statements are based on our current beliefs using information available to us as of today's date and are not intended to be guarantees of future events or performance. If our underlying assumptions turn out to be incorrect or certain risks or uncertainties materialize, actual results could vary materially from those projected by the forward looking statements. Factors that may cause such differences are discussed in our periodic reports and other filings with the SEC, including the Risk Factors section of our most recent annual report on Form 10 K. Lawson Scientific disclaims any intention or obligation to update these forward looking statements except as required by law.

Great. Well then, John, thank you everyone for joining us today. In 2024, we had an excellent performance across the board, surpassing our financial goals that we set for the year. This outstanding and differentiated performance is fueled by innovation and great execution across our global business units and the earlier than expected approval and adoption of TheraPulse in The U.

S. In fourth quarter 'twenty four, company operational sales grew 23 and organic sales grew 20%, exceeding the high end of our guidance range of 14% to 16%. Full year 2024 operational sales grew 18.5%, while organic sales grew 16% for the year, exceeding our guidance of approximately 15%. We believe that most of our global business units grew in line or faster than their respective markets in 2024, which is a testament to our broad diversified product portfolio and the winning spirit of our global teams. Fourth quarter adjusted EPS of $0.7 grew 26%, which exceeded the high end of guidance range of $0.64 to $0.66 Full year adjusted EPS of $2.51 grew 22%, also exceeding the high end range of our guidance of $2.45 to $2.47 For the year, we drove 70 basis points of adjusted operating margin to 27%, representing a balance of margin drop through and the revenue upside we saw throughout the year along with the reinvestment back into the business to drive long term differentiated growth.

For our 'twenty five outlook, we expect our differentiated financial performance to continue, fueled by our innovative portfolio and strong global execution, and we're guiding to organic growth of 14% to 16% for the first quarter of 'twenty five and ten percent to 12% for the full year. Our first quarter 'twenty five adjusted EPS guide is $0.66 to $0.68 and we expect our full year adjusted EPS to be $2.8 to $2.87 representing growth of 12% to 14%. Dan will provide more details on the financials and then I'll provide some additional highlights in 2024. So regionally, on an operational basis, The U. S.

Grew 31% in the fourth quarter. Full year 2024 was 21% with double digit growth in six of our eight business units. On an operational basis, Middle East Europe, Middle East and Africa grew 12% in the fourth quarter and 14% on the full year. In '24, we saw above market growth from all business units supported by strong commercial execution, talking about Europe here, and key franchises across the portfolio as well as price discipline. We expect to outpace the market again in 'twenty five with further momentum in EP following the recent approval of Fairwave NAV and increasing contribution from our growth in Merchant Markets.

In Asia Pac, we grew 12% operationally in fourth quarter and 16% for the full year, led by an excellent performance and double digit growth across Japan, China, Australia and New Zealand. Japan really had a nice year growing double digits for the second year in a row, driven by agent DCB, Resume, Watchmen Flex Pro and very early contribution from Farapulse. On a full year basis, China grew strong double digits across $1,000,000,000 in revenue. This differentiated growth in China was fueled by our broad portfolio, focus on innovation and excellent commercial execution. Looking ahead, we expect China to grow mid teens with increasing contribution from VERIPULS in our diverse portfolio despite the ongoing VBP pricing pressures in the region.

I'll now provide some additional commentary on our businesses. Starting with Urology, which grew 8% in fourth quarter and 9% for the full year, and operational basis grew 20% in fourth quarter and 13% for the full year, following the November close of Axonics. Full year organic growth was fueled by prosthetic urology and stone management, where we had key launches with the Tenacio pump for the AMS700 and continued success with our expanding LITHAVU portfolio. Prostate Health also performed well in 2024 with double digit growth in Rezum as well as strong performance in SPACESORE. We're pleased to have enrolled our first patient in the HydroSpace trial, evaluating the safety net efficacy of our SPACER hydrogel.

In 'twenty five, we expect to see continued strong above market growth for urology and look forward to further integrating the highly complementary Axonics Technologies into our portfolio. Endoscopy sales grew 8% operationally and 7% in the fourth quarter organically on a full year basis, grew 9% operationally and eight percent organically. Full year growth was led by double digit growth in our endoluminal surgery and single use imaging franchises, along with sustained growth of our Axios platform, where we're investing to drive expanded indications and most recently receiving approval in Japan for Axios for gallbladder drainage. Within endoluminal surgery, we continue to see positive reimbursement wins for our ESG weight loss procedure with the recent category one CPT code announced and now IFSO and international bariatric committee endorsing ESG with guideline updates. Neuromodulation sales grew 12% operationally and 5% organic in Q4 and on a full year basis grew 14% operationally and 3% organically.

Our Brain franchise grew mid single digits in both the quarter and on a full year basis and our Pain franchise grew mid single digits in the quarter and low single digits for the year. Within Deep Brain Stimulation, we expect improving growth in 2025 with the recent FDA and CE Mark approvals of our unique Cartesia X and HX leads, the first and only 16 contact directional leads that deliver precise personalized therapy. We also expect higher growth in our pain franchise in 'twenty five, driven by continued strong momentum at Intracept and the recently released data supporting safety, effectiveness and durability through five years now. Cardiology delivered an exceptional quarter and year with sales growing 32% in fourth quarter and 25% for the full year. Within cardiology, interventional cardiology therapies, sales grew 10 in fourth quarter and 11% for the full year.

And on a full year basis, the coronary therapies franchise growth was driven by strong global performance in our imaging and complex PCI franchises and earlier momentum with The U. S. Launch of agent DCB, which now has additional reimbursement in the outpatient setting. In addition, we recently announced our agreement to acquire Bolt Medical, an intravascular lithotripsy platform for treatment of coronary and peripheral artery disease. BOLT's IVL technology is highly synergistic with our existing suite of devices in complex PCI, imaging and drug loading portfolios in both ICTX and PI.

And we're excited to close the BOLT acquisition, which we expect to do so in the first half of this year. Our structural heart valves franchise grew double digits for the full year and low single digits in fourth quarter. During fourth quarter, we launched our next generation Accurate Prime valve in Europe, which features frame enhancements, simplified deployment mechanism and includes a larger valve size. Watchmen sales grew 20% in the fourth quarter and 19% on a full year basis. U.

S. Fourth Quarter growth of 20% was bolstered by an increase in concomitant procedures enabled by the new DRG, which became effective in October, and positive data from our OPTION trial demonstrating a similar stroke risk reduction with superior bleed risk reduction versus OACs in high risk patients following AF ablation. These positive outcomes from Option were reaffirmed by data in a concomitant subset of patients, which was recently presented at the AF Symposium. We're pleased with the performance of our WATCHMAN business in 2024 and expect this market to continue to grow approximately 20%, driven by concomitant procedures, ongoing clinical evidence and our initiatives to drive patient awareness and physician training. Cardiac Rhythm Management sales grew 3% in the quarter and on a full year basis.

Our diagnostics franchise grew double digits on a full year basis in outpatient market growth, driven by our implantable cardiac monitors with early contribution from our Luxe DX2 launch in Europe. In Corus CRM in both fourth quarter and on a full year basis, both our high end and low voltage business grew low single digits. And as we look ahead, we're excited to bring our EMPOWUR Legal's Pacemaker and modular Centimeters system to market in '25, likely in the second half of the year. Electrophysiology sales grew 172% in the fourth quarter and 139% on a full year basis. Therapulse has continued to lead the transformation of the AFib market, surpassing $1,000,000,000 in revenue in 2024 globally with over two hundred thousand patients treated.

And we expect the AF market to continue to rapidly convert to PFA in 'twenty five and beyond, driven by VERIPULSE. Exceptional fourth quarter sales performance was driven by VERIPULSE uptake in The U. S. And Europe as a result of very strong safety profile, ease of use and procedural efficiency, as well as our launches in both Japan and China. Initial feedback on our integrated system of Fairwave NAV on our OPAL mapping system, which we launched during the fourth quarter in The U.

S, has been very positive. We expect to continue to enhance our capabilities in this segment of the market, including with our recently closed acquisition of Cortex, an advanced AF mapping solution. We continue to build a best in class compendium of clinical evidence, including the recent results of Phase one of the ADDvantage AF trial, with data demonstrating positive outcomes using VERIPULSE in persistent AF patients, meeting the primary endpoint for efficacy and safety, with zero instances of stroke, pulmonary vein stenosis, soft visual injury or major access complications. We expect an updated label for persistent AF in the second half of the year. In the coming weeks, we expect to complete the enrollment of Avangard evaluating the safety and efficacy of VERIPULS as a first line treatment for persistent AF compared to antiarrhythmic drug therapy.

Additionally, we anticipate data to be presented in the first half of this year from Phase II of the ADDvantage AF trial evaluating FAIRAPOINT, which is our point by point PFA ablation catheter, which is expected to support U. S. FDA approval by year end 2025. Turning to peripheral interventions. Fourth quarter sales grew 22% operationally and 12% organically on a full year basis, grew 15% operationally and 11% organic.

Our interventional oncology and embolization franchise excelled again in Q4 with double digit growth across the entire product portfolio and growing mid teens for the full year. Expanding clinical evidence for new indications continues to be a focus area. We're pleased to have completed enrollment in the first phase of the FONTIER trial, which is an early feasibility study for the use of TheraSPHERE to treat recurrent glioblastoma. Additionally, we look forward to closing our acquisition of Entera, expecting the first half of twenty twenty five, which will broaden our interventional oncology offerings to patients with liver cancer. Within our vascular franchise on a full year basis, we saw high single digit arterial performance, led by double digit growth in our drug leading portfolio and mid single digit venous growth, led by Girathena in our clot management portfolio.

On a standalone basis, the Silk Road business grew double digits for the full year, and we're pleased to recently share the thirty day results from the Roadster III study, which demonstrate the safety and effectiveness of TCAR for patients with standard surgical risk. So in closing, I'm very proud of our global team and what we were able to accomplish in 2024, resulting in full year organic growth of 16% adjusted EPS growth of 22% We're very excited about the future of Boston Scientific and remain focused on our talents while enhancing our culture that is relentless in driving differentiated results. With that, I'll pass it off to Dan to provide more details on the financials.

Thanks, Mike. Fourth quarter twenty twenty four consolidated revenue of $561,004,000 represents 22.4% reported growth versus fourth quarter twenty twenty three and includes a 70 basis point headwind from foreign exchange, which was unfavorable versus our expectations.

Excluding this $26,000,000 foreign exchange headwind, operational revenue growth was 23.1% in the quarter. Sales impact from closed acquisitions contributed three sixty basis points, resulting in 19.5% organic revenue growth exceeding our fourth quarter guidance range of 14% to 16%. Q4 twenty twenty four adjusted earnings per share of $0.7 grew 26% versus 2023 exceeding the high end of our guidance range of $0.64 to $0.66 primarily driven by our strong sales performance and favorable tax results in the quarter. Full year 2024 consolidated revenue of $16,007.04 $7,000,000,000 represents 17.6% reported growth versus full year 2023 and includes a 90 basis point headwind from foreign exchange. Excluding this $127,000,000 headwind from foreign exchange, operational revenue growth for the year was 18.5%.

Sales from closed acquisitions contributed two ten basis points resulting in 16.4 organic revenue growth exceeding our guidance range of approximately 15%. Full year 2024 adjusted earnings per share of $2.51 grew 22% versus 2023, exceeding the high end of our guidance range of $2.45 to $2.47 These results include a $0.05 headwind from FX, which was slightly unfavorable to our expectations. Adjusted gross margin for the fourth quarter was 70.6%, which represents a 20 basis point sequential improvement versus the third quarter and results in full year 2024 adjusted gross margin of 70.3%. In 2025, we anticipate our full year adjusted gross margin will improve versus the full year 2024 and contribute to our adjusted operating margin expansion goals. Fourth quarter adjusted operating margin was 27.4% resulting in a full year 2024 adjusted operating margin of 27%, improving 70 basis points versus the full year 2023.

We expect to expand adjusted operating margin in 2025 by another 50 to 75 basis points, balancing differentiated operating margin expansion, while making targeted investments to fuel long term top line growth. On a GAAP basis, fourth quarter operating margin was 14.8% resulting in a full year reported operating margin of 15.5%. Moving to below the line, fourth quarter adjusted interest and other expenses totaled $87,000,000 resulting in full year adjusted interest and other expenses of $3.00 $1,000,000 in line with our expectations. On an adjusted basis, our tax rate for the fourth quarter was ten point five percent and eleven point nine percent for the full year 2024, including favorable discrete tax items and the benefit from stock compensation accounting. Our operational tax rate was 12.3% for the fourth quarter and 13.2% for the full year, again in line with expectations.

Fully diluted weighted average shares outstanding ended at 1,490,000,000.00 shares in Q4 and 1,486,000,000.000 shares for the full year 2024. Free cash flow for the quarter was $1,181,000,000,000 dollars with $1,456,000,000 from operating activities less $275,000,000 in net capital expenditures, which include payments of $177,000,000 related to acquisitions, restructuring, litigation and other special items. Full year 2024 free cash flow was $2,648,000,000 exceeding our expectations and importantly achieving 71% free cash flow conversion for the year. For 2025, we expect full year free cash flow to be in excess of $3,000,000,000 As of 12/31/2024, we had cash on hand of four fourteen million dollars and our gross debt leverage ratio was 2.2 times. Our top capital allocation priority remains strategic tuck in M and A followed by annual share repurchases.

Our legal reserve was $326,000,000 as of December 31, representing a $76,000,000 increase versus Q3 twenty twenty four. Dollars '50 million of this reserve is already funded through our qualified settlement funds. I will now walk through guidance for Q1 and the full year 2025. We expect full year 2025 reported revenue growth to be in a range of 12.5% to 14.5% versus 2024%. Excluding an approximate 100 basis point headwind from foreign exchange based on current rates, we expect full year 2025 operational growth to be in a range of 13.5% to 15.5%.

Excluding a three fifty basis point contribution from closed acquisitions, we expect full year 2025 organic revenue growth to be in a range of 10% to 12% versus 2024. We expect first quarter twenty twenty five reported revenue growth to be in a range of 17% to 19% versus the first quarter of twenty twenty four, excluding an approximate 100 basis point headwind from foreign exchange based on current rates, we expect first quarter twenty twenty five operational revenue growth to be in a range of 18% to 20%. Excluding a 400 basis point contribution from closed acquisitions, we expect first quarter twenty twenty five organic revenue growth to be in a range of 14% to 16% versus 2024. As we indicated on our October call, we had one more business day in the fourth quarter of twenty twenty four, which was worth approximately 200 basis points. In the first quarter of twenty twenty five, we have one less business day, again worth approximately 200 basis points.

When adjusting for the impact of business days, the high end of our first quarter twenty twenty five guidance range is in line with fourth quarter twenty twenty four organic revenue growth. We expect full year 2025 adjusted below the line expense to be approximately $425,000,000 Under current legislation, including enacted laws and issued guidance, we forecast a full year 2025 operational tax rate of approximately 13.5% and an adjusted tax rate of approximately 12.5%. This includes a benefit from the accounting for stock compensation, which we expect will be largely recognized in the first quarter resulting in a forecasted Q1 twenty twenty five adjusted tax rate of approximately 11.5%. We expect full year adjusted earnings per share to be in a range of $2.8 to $2.87 representing growth of 12% to 14% versus 2024 including an approximate $0.05 to $0.06 headwind from foreign exchange which is in line with what we saw in 2024. We expect first quarter adjusted earnings per share to be in a range of 0.66 to $0.68 As it relates to tariffs, we do not have significant levels of manufacturing in or sourcing from Mexico, Canada or China As such, while the recent executive actions relative to these countries could present a minor headwind for the year, we view these headwinds as manageable and they've been contemplated in our guidance ranges.

In closing, I'm extremely proud of what our global team delivered for 2024 financial performance and look forward to executing on our full year 2025 guidance of 10% to 12% organic revenue growth, 50 to 75 basis points of adjusted operating margin expansion and 12% to 14% adjusted EPS growth. For more information, please check our Investor Relations website for Q4 twenty twenty four financial and operational highlights, which outlines more details on Q4 results and 2025 guidance. And with that, I'll turn it back to John to moderate the Q

Thanks, Dan. Drew, let's open it up for questions for the next thirty five minutes or so. In order for us to take as many questions as possible, please limit yourself to one question. Drew, please go ahead.

The first question comes from Robbie Marcus with JPMorgan. Please go ahead.

Great. Good morning and congratulations on a really good fourth quarter.

on PFA and WATCHMAN. You had very good fourth quarters here, saw a slight tick up in U. S. Growth in WATCHMAN. Would love to get your thoughts on sort of what you saw during the quarter after con commitment reimbursement kicked in October 1 and the OPTION trial and how you're thinking specifically about those products throughout 2025 given their two year better margin products and the implications?

Thanks, Robbie. Yes, we have excellent momentum in both VERIPULSE and WATCHMAN, increasing momentum, I would say. With WATCHMAN, we did see a bit of a benefit at the end of the fourth quarter with the concomitant news, which reconfirmed based on the option trial data safety and efficacy with the reimbursement. We saw a little bit of uptick. As we stated before, we think the concomitant reinforces the 20% market CAGR for 2025.

And we'll be excited about the option readout in the first half of twenty twenty six. So we're well positioned with WATCHMAN and we obviously continue to invest in our product portfolio, clinical evidence, our clinical teams around the world to fully maximize the concomitant opportunity and obviously with the momentum of Therapulse in our broader Rhythm Management portfolio, ideally becoming the partner of choice for AFib and electrophysiologists. The Therapulse, I think the numbers pretty stand out. Tremendous growth is the biggest transformation that I've seen in MedTech, over $1,000,000,000 globally in one year. We launched less than a year ago in The U.

S. So that the execution of our commercial teams has been strong. The execution of our investments that we made throughout the year. So we're excited about our competitive position with Farepulse in 2025. You've seen the clinical data.

It's a bit unclear as to the competitive landscape in 2025, But we put that aside and we push every day to invest in our commercial execution, our R and D and we want to become the clear leader as we are now in PFA as PFA is really transforming this market.

The next question comes from Larry Biegelsen with Wells Fargo. Please go ahead.

Good morning. Thanks for taking the question and I'll echo my congratulations. Obviously a stellar quarter and year. Mike and Dan, I was hoping to ask one kind of long term question. At JPMorgan, you increased your weighted average market growth to 9% in 2026.

And I know you expect to grow faster than your end market. So does this imply you see Boston as at least a 9% grower in 2026? And can you grow EPS double digits next year with the tax rate increasing, Dan, two hundred to 300 basis points? Thanks a lot.

Sure. Obviously, we're not going to give any specific guidance relative to anything beyond 2025. But I think safe to assume, as we've done over the last decade very well as a team, we seek to outgrow our end market. So as those grow at at an increasing rate, we still look to outgrow those markets. So I would stay tuned as we get through the year, potentially have an Investor Day at the end of this year and reset those goals for the long term.

But we're excited if you look over the last decade to see the increase in that WAMGR very intentionally over that timeframe with both internal investments as well as smart tuck in acquisitions to get to that 9% by 2026. Relative to double digit EPS, again, I point to the track record, extremely strong record of double digit adjusted EPS growth. That's always the goal. We'll see what happens to the tax rate. That could be obviously a fluid environment in Washington.

So if there's even an increase in that tax rate, our goal will still be to get double the GDP growth in 2026 and beyond.

The next question comes from Rick Wise with Stifel. Please go ahead.

Good morning, everybody, and thanks for the great quarter. Maybe it's a 1.25 of a question. You typically start the year in what I like to call prudently conservative fashion in recent years. Maybe you can help us better understand where the upsides and where the risks are and should we view this as another attempt to start the year in a thoughtfully prudently conservative fashion? And related to that, I mean, how are you thinking about competition on the PFIA side coming in?

What's dialed into your guidance as of this point? Thank you.

Hey, Rick. You certainly want us to be thoughtful and prudent, which we always are in our guidance and we have a nice track record of delivering on our commitments. So I would say that's the same strategy as we provided the guide in 2025. Clearly, the company has a lot of momentum. I would say we do have more tailwinds than headwinds.

When you think about the tailwinds, there's a lot of momentum across every region. You obviously know about the fair pulse momentum in The U. S. And we're early days of our launch in Japan and China, dominant. Really a big shout out to our coronary team, ICTX with agent launch and other businesses like IO growing mid teens and our Endo Euro, PI Neuromod business, all very solid growth and we expect Neuromod to be above market in 2025.

So strong momentum there on the tailwind side. There could be stronger PFA competition in 2025. A lot of that is out of our hands, but we as I said before, we're focused on driving forward relentlessly every day. China BPP is more extensive this year in 2025 than it has been in the past. But despite that, we expect to grow kind of mid teens in China in 2025, but that will be a little more difficult for us this year.

And there are some continuing strengthening lower cost competitors, I would say, for some of our MedSurg businesses in Asia and in Europe. And the team focused on our portfolio and innovation to counteract that, but that is a bit of a headwind for us in our endo in Europe business. But overall, we feel overall that we certainly we do have more tailwinds and headwinds and we are looking forward to the year.

The next question comes from Joanne Wuensch with Citibank. Please go ahead.

Good morning and nice end to the year. I want to spend just a little bit of time talking about margins. Interesting commentary on gross margins being additive to the operating margin expansion. I'm sort of curious how do you think about managing that? And I'm going to sneak in a cash flow question.

You're kicking out a lot of cash. How do you think about investing it? Thank you.

Sure, Joanna. I can take that. I'll tell you what I really like about 2025 is the equation for the operating margin expansion. We've done it very well over the last decade each year with a variety of different scenarios. But I think one of the optimal scenarios is where gross margin goes north, SG and A you get leverage and then I think in 2025, you might actually see a little bit of an uptick in R and D spend as a percentage of sales.

I think that's a winning hand for how to increase operating margin overall. And so in our 50 to 75 basis points, I'd look for gross margin to get better versus the 70.3 that we put up in 2024. I'd look for SG and A on the 10% to 12% sales growth to improve its leverage there and deliver margin expansion. And then again on R and D, not a significant increase, but maybe 20 basis points of an uptick in R and D to continue to help to fuel the top line growth for the long term. I think that's a great equation for 25% for margin expansion.

Cash flow, you saw and you heard in the commentary, we got to 71% free cash flow conversion. That wasn't by accident. That's a tremendous effort by the entire global team on reducing DIOH, reducing DSO, strong working capital management and of course, obviously significant growth in operating income. In terms of our capital allocation strategy, no change. It's worked well for us again over the last decade to have the number one priority for use of our cash to be high quality tuck in innovative M and A that will continue and then annual share repurchase after that.

We ended the year at 2.2 times debt after the Axonics and Silk Road acquisitions. So we're in a real great spot to continue to do that strategy and execute that strategy in 2025 and beyond.

The next question comes from David Roman with Goldman Sachs. Please go ahead.

Thank you. Good morning, everybody. I wanted just to dive into some of the different drivers here around the EP business. Clearly, on the Farewell side, you've seen huge conversion on that de novo, Paraxysmal segment of the market. But as you gain a persistent indication and then also launch Fairpoint exiting 2026, Can you maybe help us think about the segment of the market that you're not able to address today and how much market becomes available to you with Fairpoint and the persistent indication?

And then maybe as a corollary to that, help us think through kind of the mapping strategy given your installed base relative to the other two participants in the market and how you're thinking about remaining an open platform versus potentially looking to become more closed on as some of your peers are?

Yes. Thanks, Dave. I'm going to start with the mapping strategy first. Again, I guess as you point out, right, we intend to maintain an open platform. We don't need to force people to use our Opal mapping system.

And I think it's actually really important as we look both at how the business evolves globally as well as we look at potential future moves into like an ASC type environment to be able to support doing cases without mapping, to be able to support doing cases with competitive mapping systems, but also to provide differentiated features within Opel and our Fairview software package that I think really provide the best possible solution for people who want to map their cases. And even though it's early into the launch of Fairwave Nav and Fairview in The U. S, we've really been very pleased with the feedback that we've gotten thus far. In terms of drivers, I'm important to acknowledge, right, that the persistent atrial fibrillation population, just in prevalence terms, is at least as large and probably larger than the population with paroxysmal atrial fibrillation. I'd also acknowledge that we are already seeing off label use of Farapulse in treating patients with atrial with persistent atrial fibrillation.

That's why it was important for us to run trials like ADDvantage and Avant Garde. I think everyone's seen the data from the ADDvantage trial in all of our endpoints in terms of safety and efficacy in treating persistent atrial fibrillation. And so we do anticipate getting that label by the end of this year. Beyond that, right, then the next drivers in terms of at least to expanding our labeling, as you say, getting Farpoint to be used as an adjunct for treating atrial flutter in patients who are undergoing ablation for atrial fibrillation, Avant Garde moving to first line therapy and also our REMATCH trial, which will qualify labeling beyond de novo use, but use in patients who are undergoing repeat AF ablation procedures.

The next question comes from Travis Steed with Bank of America. Please go ahead.

Hey, congrats on the quarter and also thanks for posting the slide deck early on. That was really helpful. I wanted to ask about M and A strategy now that you're kind of annualizing kind of $17,000,000,000 in revenue and that revenue base is growing so fast so much faster. Like how do you balance that it's going to take a larger deal to kind

a larger revenue base, but also finding growth accretive deals that now that your baseline growth is so much faster already, just kind of thinking about like how your M and A strategy changes now that you're a bigger company and growing so much faster?

It doesn't change that much. We're always investing for the long term at Boston Scientific. We obviously gave 25 guide, but as we've said before at another conference in January, we're investing for products that won't be launched until 02/1930 through internal organic M and A through our VC portfolio, which is very extensive. We did nine new investments in our VC portfolio in 2025. And you're aware of the tuck in acquisitions that we've done in 2025, '4 or five of those.

And so the formula remains. We really are focused on increasing our WAM growth, which was Dan talked about earlier, which we anticipate 9% in 2026, growing faster than that WAMGAR and consistently quarter by quarter, year over year, doing everything we can to enhance that WAMGAR through those tools of internal R and D, VC portfolio and tech and M and A. So as the company gets larger, it's become larger every year and we continue to find ways to improve our WAMGR and exceed the growth of our WAMGR. So we placed a lot of focus and time internally on ensuring that we'll be a differentiated company in 02/1930 beyond 2025.

The next question comes from Patrick Wood with Morgan Stanley. Please go ahead.

Beautiful. I'd love to just broaden out a little bit. I appreciate the endoscopy business is kind of singles and doubles, but obviously you guys have been flagging Apollo ESG. Quite a unique approach under Luminol. I'm super curious, even though they're down a bit, there's a chunk of sleeves that are still done in The U.

S. And it seems like a way better approach. I'm super curious how you think mid term, how big that business could be? How you're feeling about the initial launch there? Just anything you got to give us on ESG, I'd love to hear it.

Yes. I would say that ties to the previous question. We're investing in ESG now. We have a dedicated team that our group has organized on the ESG product around Apollo. We have dedicated clinical trials to broaden that indication out and improve the clinical science behind it.

We have some recent momentum with CPT codes. So it's going to be a nice driver over the long term for endo business. It's not going to reshape Boston Scientific Endo in 2025, but we definitely see a positive support by the physicians, by the industry groups, by the reimbursements. We're unique and we're likely the only one who can offer the APOLLO procedure wrapped around with our other endo tools. So we think this will be a significant growth driver for endo as you look towards the kind of longer term in the strap plan.

The next question comes from Danielle Antalffy with UBS. Please go ahead.

Hey, good morning, everyone. Thanks so much for taking the question. Congrats on a really strong year. Just a quick question at a high level. We talk we focus so much on the major growth drivers like Therapolz and Watchmen.

I'm just curious, Mike or Dan, where you think Boston Scientific is either underperforming or under indexed, but see improving performance over the next year or two that maybe the street under modeling or not appreciating? Thanks so much.

Yes. So most of our businesses did well against the peer group in the market growing faster than CAGR. Even if you take out WATCHMAN and VERIPULSE results, the rest of the businesses grew faster than our WAMGR. A couple of areas that we want to improve on in 2025, '1 is the overall Neuromod performance, which we anticipate will have a nice improvement in 2025. With the launch in our DBS platform, we expect that to gain momentum in 2025 and the combination of our refocused commercial team in pain and the benefit of Relivant.

So we do anticipate a better year for Neuromod. We want to strengthen U. S. CRM. We continue to maintain share, I would say, in terms of the unit volume perspective and high voltage.

We don't have the portfolio yet in Leadless Pacemaker, which has a strong higher ASP, which is driving on a dollar basis share loss in PACER. So we'd like to see improvement in our overall U. S. CRM business. We're launching SICD with Legalist Pacemaker in the tail half of 2025 and we'll have increased focus on that business in 2025.

So we'd like to see some improvements there. And as I mentioned before, we do see some increasing competition in some of our businesses from the lower cost competitors. So we're challenging our team to continue to drive a lower cost portfolio, so we can serve our global customers more efficiently.

The next question comes from Michael Pollack with Wolfe Research. Please go ahead.

to ask on the TAVR or the structural heart update in the deck, low single digit growth in the fourth quarter. Can you just comment on kind of post accurate IDE? Is that the influence that's driving the decel there? Or are there other things you'd call out? And then maybe Pester for an update on the path in The U.

Boston Scientific (BSX) Q4 2024 Earnings Call Transcript

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