The statement, even for Trump, was a shocking comment that came as police were still investigating the deaths of the director and his wife, Michele Singer Reiner, as an apparent homicide. The couple were found dead at their home Sunday in Los Angeles. Investigators believe they suffered stab wounds and the couple’s son Nick Reiner was in police custody early Monday.

Trump has a long track record of inflammatory remarks, but his comments in a social media post were a drastic departure from the role presidents typically play in offering a message of consolation or tribute after the death of a public figure. His message drew criticism even from conservatives and his supporters and laid bare Trump’s unwillingness to rise above political grievance in moments of crisis.

Trump, in a post on his social media network, said Reiner and his wife were killed “reportedly due to the anger he caused others through his massive, unyielding, and incurable affliction with a mind crippling disease known as TRUMP DERANGEMENT SYNDROME.”

He said Reiner “was known to have driven people CRAZY by his raging obsession of President Donald J. Trump, with his obvious paranoia reaching new heights as the Trump Administration surpassed all goals and expectations of greatness.”

The president did not mention his personal connection to Reiner’s wife, who was a photographer. Peter Osnos, the original publisher of “The Art of the Deal,” confirmed Monday that Michele Singer took the cover image of Trump’s 1987 bestseller.

Kentucky Republican Rep. Thomas Massie, who has bucked much of his party’s lockstep agreement with the president, criticized Trump for the comment.

“Regardless of how you felt about Rob Reiner, this is inappropriate and disrespectful discourse about a man who was just brutally murdered,” Massie wrote in a post on X. “I guess my elected GOP colleagues, the VP, and White House staff will just ignore it because they’re afraid? I challenge anyone to defend it.”

Rep. Marjorie Taylor Greene, a Georgia Republican whom Trump branded a “traitor” for disagreeing with him, responded to Trump’s message by saying, “This is a family tragedy, not about politics or political enemies.”

Republican Reps. Mike Lawler of New York and Stephanie Bice of Oklahoma, who are not known for pushing back on the White House, also criticized Trump’s message.

Reiner — a director of beloved films like “The Princess Bride” and “When Harry Met Sally” — was one of the most active Democrats in the film industry and regularly campaigned on behalf of liberal causes and hosted fundraisers. He was a vocal critic of Trump, calling him in a 2017 interview with Variety “mentally unfit” to be president and “the single-most unqualified human being to ever assume the presidency of the United States.”

The White House, which shared the president’s post, did not respond to a message about the criticism it was receiving and calls for Trump to take it down.

Speaking at the White House to reporters later Monday, Trump doubled down on his criticism of Reiner when he was asked if he stood by his post. Using the third person, Trump said Reiner “was a deranged person as far as Trump is concerned.”

“I was not a fan of Rob Reiner at all, in any way shape or form,” Trump said. “I thought he was very bad for our country.”

The unsympathetic message was the latest example of Trump’s unsparing prism through which he views those he perceives as enemies.

He made retribution against political enemies a prime focus of his campaign for the White House last year. And he has in the past made light of violence when it’s befallen those on the other side of the political aisle.

When Nancy Pelosi’s husband, Paul Pelosi, was attacked by an intruder looking for the former House speaker at the family’s San Francisco home in 2022 and beaten over the head with a hammer, Trump later mocked the attack.

That’s despite his comments after the assassination of conservative activist Charlie Kirk earlier this year. Trump said Kirk’s killing was “the tragic consequence of demonizing those with whom you disagree.”

His administration then sought consequences for people who were critical of Kirk or even celebrated his killing.

Jenna Ellis, who was one of Trump’s lawyers and worked on his efforts in 2020 to overturn the results of the presidential election, pointed out Trump’s double standard and called his post “NOT the appropriate response.”

“The Right uniformly condemned political and celebratory responses to Charlie Kirk’s death. This is a horrible example from Trump (and surprising considering the two attempts on his own life) and should be condemned by everyone with any decency,” Ellis said in a post on X.

When Trump spoke at Kirk’s memorial service, he used his remarks to underline how he views his adversaries.

“I hate my opponent,” the president said.

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Associated Press writer Hillel Italie in New York contributed to this report.