• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
AIdigital transformation

AI came from tech, but the most advanced AI businesses are in every industry

By
John Kell
John Kell
Contributing Writer and author of CIO Intelligence
Down Arrow Button Icon
By
John Kell
John Kell
Contributing Writer and author of CIO Intelligence
Down Arrow Button Icon
October 7, 2025, 4:45 AM ET
17 sectors outside of tech were included in the AIQ 50 list.
17 sectors outside of tech were included in the AIQ 50 list.Illustration by Simon Landrein

When Fortune published its AIQ 50 list, ranking the Fortune 500 companies that have made the most progress generating a significant impact with artificial intelligence, it perhaps came as no surprise that this cohort would be led by an AI hyperscaler, Google parent Alphabet.

Other tech giants featured on the list included Nvidia, Amazon, Microsoft, and Meta Platforms, a contingent that’s spending tens of billions of dollars annually to develop large language models and AI chips to get a competitive edge in the AI arms race.

But the AIQ 50 wasn’t only dominated by the tech sector. In fact, there were 17 other sectors with representation, including financials, health care, retail, energy, and transportation.

This expansive embrace and quick adoption of generative AI differs from past technological advancements. The widespread adoption of the internet in the late 1990s caught many industries completely off guard, including physical retail and banking. More recently, the expensive and complex IT-led shift to cloud computing saw multiple sectors lag behind, including airlines, agricultural producers, and hospitals. 

Kate Smaje, a senior partner at consulting giant McKinsey, says that unlike other digital transformation efforts, with AI there have been notable winners and losers within each sector, rather than entire industries falling behind on adoption.

AI, Smaje says, “it’s something that is innately democratized to everyone across the organization. It doesn’t matter whether you’re at the front line, you’re the HR director, or you’re the CEO. Your ability to use it and figure out ways to improve your lot, as it were, is a lot easier.”

Pharmaceutical giant Johnson & Johnson, which ranked 36 on the AIQ 50 list, has applied AI and machine learning models across all parts of the company’s business, ranging from how it recruits patients to enroll in clinical trials to reimagining the supply chain and helping surgeons perform procedures. 

Jim Swanson, J&J’s chief information officer, says that the company created a “lighthouse” framework to organize how it thinks about the value it can extract from AI across the business.

At the top of the lighthouse are use cases that apply to core products and services, including the use of AI to improve surgical outcomes. The middle layer focuses on utilizing AI to improve functions like customer support or patient enrollment in drug trials, while the lowest level involves employee productivity tools. In each case, Swanson says, he prioritizes investments that can generate big outcomes.

“What I try to look for is not the 3% to 5% incremental improvements,” says Swanson. “Can we do 30%, 40%, or 50% transformation change?”

Amanda Luther, a managing director and senior partner at consultancy Boston Consulting Group, says that the companies that are furthest along on AI tend to be investing in “three-ish” major initiatives. 

“Three tends to be kind of the magic number for the big bets you are placing,” says Luther. “Those are the ones that are getting the most ROI.”

BCG recently published a study of more than 1,250 global companies that found that only 5% of those companies had achieved AI value “at scale,” that is, firms that were seeing revenue increases or cost reductions from their AI investments beyond many of their peers.

Luther says there were five factors that led to that outperformance: a CEO-led multiyear strategic vision, an emphasis on redesigning entire workflow processes, joint ownership of IT and the various business functions, investments in talent, and finally the technology and data that underpins the entire AI ecosystem.

That CEO vision on AI was on display last month when J&J chairman and CEO Joaquin Duato appeared on CNBC to discuss the impact of tariffs on pharmaceutical imports, while also lauding future innovation advancements that can be possible thanks to AI.

“I believe we are entering into an era in which the combination of our advancements in biology and chemistry, amplified by artificial intelligence, are going to give us cures for many diseases that we thought were incurable,” Duato told Jim Cramer during the interview.

At McKinsey, Smaje says that the firm finds that the corporations that are seeing the most success with AI adoption need more than just a CEO leading the charge. “Yes, I need a great visionary CEO, but it’s not enough,” says Smaje. “I’ve got to have the full top team as well.”

Senior leaders at J&J have been regular practitioners of AI, including an AI tool that helps the executive team prepare for investor relations calls. Senior leaders have been organized in AI and data councils to guide and shape AI applications and ensure ethical policies are followed. 

On the talent front, Swanson says that more than 100,000 employees have taken the company’s generative-AI training courses, while 15,000 have enrolled in a digital boot camp. 

And while not every business function at J&J is on the same level of AI maturity, Swanson says he’s okay with that.

“It’s not chasing tech for tech. It always starts with the problem to be solved, and then what’s the right process and solution to go after,” says Swanson. “That discipline has helped us scale and be effective.”

Read more lessons from the Fortune AIQ 50, the latest Fortune AIQ special report. This collection of stories details how companies on the inaugural Fortune AIQ 50 list have made significant progress integrating artificial intelligence technology into their operations, leading to real impact.

About the Author
By John KellContributing Writer and author of CIO Intelligence

John Kell is a contributing writer for Fortune and author of Fortune’s CIO Intelligence newsletter.

See full bioRight Arrow Button Icon

Latest in AI

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in AI

Shark Tank’s Kevin O’Leary wants to build a massive $100 billion data center in rural Utah. Residents are revolting
AIData centers
Shark Tank’s Kevin O’Leary wants to build a massive $100 billion data center in rural Utah. Residents are revolting
By Marco Quiroz-GutierrezMay 11, 2026
5 minutes ago
Nvidia CEO Jensen Huang
Economyconstruction
Jensen Huang’s message to electricians and plumbers: ‘This is your time,’ as AI buildout leads to soaring demand for skilled trades
By Tristan BoveMay 11, 2026
2 hours ago
worker alone in empty office
Future of WorkTech
AI isn’t paying off in the way companies think. Layoffs driven by automation are failing to generate returns, study finds
By Jake AngeloMay 11, 2026
2 hours ago
The widow of a man killed in a Florida mass shooting is suing ChatGPT maker OpenAI, claiming it ‘knew this would happen’
LawOpenAI
The widow of a man killed in a Florida mass shooting is suing ChatGPT maker OpenAI, claiming it ‘knew this would happen’
By The Associated Press and Jeff MartinMay 11, 2026
4 hours ago
‘It’s here’: Google issues dire warning after catching hackers using AI to break into computers
AIGoogle
‘It’s here’: Google issues dire warning after catching hackers using AI to break into computers
By Matt O'Brien and The Associated PressMay 11, 2026
4 hours ago
drew
CommentaryDefense
I helped build the Pentagon’s AI transformation. Corporate America is making every mistake we almost made
By Drew CukorMay 11, 2026
5 hours ago

Most Popular

‘This is the way’: Elon Musk endorses Warren Buffett’s famed 5-minute plan to fix the national debt
Economy
‘This is the way’: Elon Musk endorses Warren Buffett’s famed 5-minute plan to fix the national debt
By Jacqueline MunisMay 10, 2026
1 day ago
OpenAI CEO Sam Altman says Gen Z and millennials are using ChatGPT like a 'life advisor'—but college students might be one step ahead
Tech
OpenAI CEO Sam Altman says Gen Z and millennials are using ChatGPT like a 'life advisor'—but college students might be one step ahead
By Sydney LakeMay 10, 2026
1 day ago
Red flag test: former CEO explains why he rejects job candidates who say they can start right away
Success
Red flag test: former CEO explains why he rejects job candidates who say they can start right away
By Orianna Rosa RoyleMay 9, 2026
2 days ago
'Employers are increasingly turning to degree and GPA' in hiring: Recruiters retreat from ‘talent is everywhere,’ double down on top colleges
Future of Work
'Employers are increasingly turning to degree and GPA' in hiring: Recruiters retreat from ‘talent is everywhere,’ double down on top colleges
By Jake AngeloMay 9, 2026
2 days ago
Trump thinks he's flying to Beijing with leverage. China spent 6 years making sure he doesn't have any
Commentary
Trump thinks he's flying to Beijing with leverage. China spent 6 years making sure he doesn't have any
By Steve H. HankeMay 10, 2026
1 day ago
Ted Cruz says the quiet part out loud: Trump accounts are Social Security personal accounts as GOP senator reveals 'dirty little secret'
Politics
Ted Cruz says the quiet part out loud: Trump accounts are Social Security personal accounts as GOP senator reveals 'dirty little secret'
By Jason MaMay 9, 2026
2 days ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.