• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
AI

Anthropic CEO Dario Amodei escalates war of words with Jensen Huang, calling out ‘outrageous lie’ and getting emotional about father’s death

Nick Lichtenberg
By
Nick Lichtenberg
Nick Lichtenberg
Business Editor
Down Arrow Button Icon
Nick Lichtenberg
By
Nick Lichtenberg
Nick Lichtenberg
Business Editor
Down Arrow Button Icon
August 1, 2025, 6:05 AM ET
Dario Amodei
Anthropic CEO Dario Amodei.Stefan Wermuth/Bloomberg via Getty Images

The doomers versus the optimists. The techno-optimists and the accelerationists. The Nvidia camp and the Anthropic camp. And then, of course, there’s OpenAI, which opened the Pandora’s Box of artificial intelligence in the first place.

Recommended Video

The AI space is driven by debates about whether it’s a doomsday technology or the gateway to a world of future abundance, or even whether it’s a throwback to the dotcom bubble of the early 2000s. Anthropic CEO Dario Amodei has been outspoken about AI’s risks, even famously predicting it would wipe out half of all white-collar jobs, a much gloomier outlook than the optimism offered by OpenAI’s Sam Altman or Nvidia’s Jensen Huang in the past. But Amodei has rarely laid it all out in the way he just did on tech journalist Alex Kantrowitz’s Big Technology podcast on July 30.

In a candid and emotionally charged interview, Amodei escalated his war of words with Nvidia CEO Jensen Huang, vehemently denying accusations that he is seeking to control the AI industry and expressing profound anger at being labeled a “doomer.” Amodei’s impassioned defense was rooted in a deeply personal revelation about his father’s death, which he says fuels his urgent pursuit of beneficial AI while simultaneously driving his warnings about its risks, including his belief in strong regulation.

Amodei directly confronted the criticism, stating, “I get very angry when people call me a doomer … When someone’s like, ‘This guy’s a doomer. He wants to slow things down.'” He dismissed the notion, attributed to figures like Jensen Huang, that “Dario thinks he’s the only one who can build this safely and therefore wants to control the entire industry” as an “outrageous lie. That’s the most outrageous lie I’ve ever heard.” He insisted that he’s never said anything like that.

His strong reaction, Amodei explained, stems from a profound personal experience: his father’s death in 2006 from an illness that saw its cure rate jump from 50% to roughly 95% just three or four years later. This tragic event instilled in him a deep understanding of “the urgency of solving the relevant problems” and a powerful “humanistic sense of the benefit of this technology.” He views AI as the only means to tackle complex issues like those in biology, which he felt were “beyond human scale.” As he continued, he explained how he’s actually the one who’s really optimistic about AI, despite his own doomsday warnings about its future impact.

Who’s the real optimist?

Amodei insisted that he appreciates AI’s benefits more than those who call themselves optimists. “I feel in fact that I and Anthropic have often been able to do a better job of articulating the benefits of AI than some of the people who call themselves optimists or accelerationists,” he asserted.

In bringing up “optimist” and “accelerationist,” Amodei was referring to two camps, even movements, in Silicon Valley, with venture-capital billionaire Marc Andreessen close to the center of each. The Andreessen Horowitz co-founder has embraced both, issuing a “techno-optimist manifesto” in 2023 and often tweeting “e/acc,” short for effective accelerationism.

Both terms stretch back to roughly the mid-20th century, with techno-optimism appearing shortly after World War II and accelerationism appearing in the science-fiction of Roger Zelazny in his classic 1967 novel “Lord of Light.” As Andreessen helped popularize and mainstream these beliefs, they roughly add up to an overarching belief that technology can solve all of humanity’s problems. Amodei’s remarks to Kantrowitz revealed much in common with these beliefs, with Amodei declaring that he feels obligated to warn about the risks inherent with AI, “because we can have such a good world if we get everything right.”

Amodei claimed he’s “one of the most bullish about AI capabilities improving very fast,” saying he’s repeatedly stressed how AI progress is exponential in nature, where models rapidly improve with more compute, data, and training. This rapid advancement means issues such as national security and economic impacts are drawing very close, in his opinion. His urgency has increased because he is “concerned that the risks of AI are getting closer and closer” and he doesn’t see that the ability to handle risk isn’t keeping up with the speed of technological advance.

To mitigate these risks, Amodei champions regulations and “responsible scaling policies” and advocates for a “race to the top,” where companies compete to build safer systems, rather than a “race to the bottom,” with people and companies competing to release products as quickly as possible, without minding the risks. Anthropic was the first to publish such a responsible scaling policy, he noted, aiming to set an example and encourage others to follow suit. He openly shares Anthropic’s safety research, including interpretability work and constitutional AI, seeing them as a public good.

Amodei addressed the debate about “open source,” as championed by Nvidia and Jensen Huang. It’s a “red herring,” Amodei insisted, because large language models are fundamentally opaque, so there can be no such thing as open-source development of AI technology as currently constructed.

An Nvidia spokesperson, who provided a similar statement to Kantrowitz, told Fortune that the company supports “safe, responsible, and transparent AI.” Nvidia said thousands of startups and developers in its ecosystem and the open-source community are enhancing safety. The company then criticized Amodei’s stance calling for increased AI regulation: “Lobbying for regulatory capture against open source will only stifle innovation, make AI less safe and secure, and less democratic. That’s not a ‘race to the top’ or the way for America to win.” 

Anthropic reiterated its statement that it “stands by its recently filed public submission in support of strong and balanced export controls that help secure America’s lead in infrastructure development and ensure that the values of freedom and democracy shape the future of AI.” The company previously told Fortune in a statement that “Dario has never claimed that ‘only Anthropic’ can build safe and powerful AI. As the public record will show, Dario has advocated for a national transparency standard for AI developers (including Anthropic) so the public and policymakers are aware of the models’ capabilities and risks and can prepare accordingly.”

Kantrowitz also brought up Amodei’s departure from OpenAI to found Anthropic, years before the drama that saw Sam Altman fired by his board over ethical concerns, with several chaotic days unfolding before Altman’s return.

Amodei did not mention Altman directly, but said his decision to co-found Anthropic was spurred by a perceived lack of sincerity and trustworthiness at rival companies regarding their stated missions. He stressed that for safety efforts to succeed, “the leaders of the company … have to be trustworthy people, they have to be people whose motivations are sincere.” He continued, “if you’re working for someone whose motivations are not sincere who’s not an honest person who does not truly want to make the world better, it’s not going to work you’re just contributing to something bad.”

Amodei also expressed frustration with both extremes in the AI debate. He labeled arguments from certain “doomers” that AI cannot be built safely as “nonsense,” calling such positions “intellectually and morally unserious.” He called for more thoughtfulness, honesty, and “more people willing to go against their interest.”

For this story, Fortune used generative AI to help with an initial draft. An editor verified the accuracy of the information before publishing. 

In 2001, Fortune first convened “The Smartest People We Know,” bringing together CEOs and founders, builders and investors, thinkers and doers. Since then, Fortune Brainstorm Tech has been the place where bold ideas collide. From June 8–10, we will return to Aspen—where it all began—to mark 25 years of Brainstorm. Register now.
About the Author
Nick Lichtenberg
By Nick LichtenbergBusiness Editor
LinkedIn icon

Nick Lichtenberg is business editor and was formerly Fortune's executive editor of global news.

See full bioRight Arrow Button Icon

Latest in AI

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • Future 50
  • World’s Most Admired Companies
  • See All Rankings
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • About Us
  • Editorial Calendar
  • Press Center
  • Work At Fortune
  • Diversity And Inclusion
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in AI

Bernard Looney, CEO of Prometheus Hyperscale
EnergyBP
Former BP CEO takes over Wyoming data center developer, as first woman leader of Big Oil giant becomes new BP chief
By Jordan BlumMarch 31, 2026
10 hours ago
brian
CommentaryCulture
The real engine of innovation is trust
By Brian DoublesMarch 31, 2026
12 hours ago
The green head of what appears to be an alien pokes out from behind a rock set against a rural landscape with a power pylon in the background.
NewslettersEye on AI
AI’s ability to see ‘mirages’ shows how alien machine brains really are
By Jeremy KahnMarch 31, 2026
13 hours ago
Anthropic mistakenly leaks its own AI coding tool’s source code, just days after accidentally revealing an upcoming model known as Mythos
AIAnthropic
Anthropic mistakenly leaks its own AI coding tool’s source code, just days after accidentally revealing an upcoming model known as Mythos
By Beatrice NolanMarch 31, 2026
13 hours ago
The beauty counter is now on your For You page as Ulta Beauty joins TikTok Shop, betting on the platform reshaping how America consumes
RetailTikTok
The beauty counter is now on your For You page as Ulta Beauty joins TikTok Shop, betting on the platform reshaping how America consumes
By Catherina GioinoMarch 31, 2026
14 hours ago
Business man shakes hand
SuccessCareers
As AI threatens to replace tech jobs, startups are desperate for top talent—and some firms are paying tech-savvy grads over $300,000
By Preston ForeMarch 31, 2026
15 hours ago

Most Popular

Jerome Powell says the $39 trillion national debt is ‘not unsustainable,’ but warns the trajectory ‘will not end well’
Economy
Jerome Powell says the $39 trillion national debt is ‘not unsustainable,’ but warns the trajectory ‘will not end well’
By Fortune EditorsMarch 30, 2026
1 day ago
A man used AI to call 3,000 Irish bartenders to track the cost of Guinness. Now pubs are lowering their prices to compete
AI
A man used AI to call 3,000 Irish bartenders to track the cost of Guinness. Now pubs are lowering their prices to compete
By Fortune EditorsMarch 30, 2026
2 days ago
Markets cheer as Trump threatens to abandon Iran war, but Jamie Dimon sides with allies: ‘Win this thing and clean up the straits’
Energy
Markets cheer as Trump threatens to abandon Iran war, but Jamie Dimon sides with allies: ‘Win this thing and clean up the straits’
By Fortune EditorsMarch 31, 2026
17 hours ago
The federal government shed 385,000 employees last year. Now the Trump administration is on a blitz to hire Gen Z workers
Politics
The federal government shed 385,000 employees last year. Now the Trump administration is on a blitz to hire Gen Z workers
By Fortune EditorsMarch 31, 2026
1 day ago
A CEO trying to reindustrialize America says blue-collar pay is headed for 'massive hyperinflation' and kids should skip college to become welders
Success
A CEO trying to reindustrialize America says blue-collar pay is headed for 'massive hyperinflation' and kids should skip college to become welders
By Fortune EditorsMarch 30, 2026
2 days ago
Current price of gold as of March 30, 2026
Personal Finance
Current price of gold as of March 30, 2026
By Fortune EditorsMarch 30, 2026
2 days ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.