• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia

Trendingnow

1

The Pentagon said Iran War costs $29 billion, but the real cost is closer to $200 billion—and counting

2

After forcing workers back to the office, Goldman Sachs and JPMorgan Chase are now letting their staff work remotely—but only for the World Cup

3

Amazon's record Prime Day masks a darker truth: Americans are spending more and getting less

1

The Pentagon said Iran War costs $29 billion, but the real cost is closer to $200 billion—and counting

2

After forcing workers back to the office, Goldman Sachs and JPMorgan Chase are now letting their staff work remotely—but only for the World Cup

3

Amazon's record Prime Day masks a darker truth: Americans are spending more and getting less
NewslettersBrainstorm Health

Is Loneliness Driving the Opioid Epidemic?

By
Sy Mukherjee
Sy Mukherjee
Down Arrow Button Icon
By
Sy Mukherjee
Sy Mukherjee
Down Arrow Button Icon
December 11, 2019, 6:04 PM ET
Add Fortune on Google for similar content.

This is the web version of Brainstorm Health Daily, Fortune’s daily newsletter on the top health care news. To get it delivered daily to your in-box, sign up here.

Good afternoon, readers.

Loneliness is a scourge. It can be nebulous and difficult to pin down. But its effects are all around us—particularly in the health care arena. Retail giant Home Depot, of all firms, is adding to that conversation, suggesting that opioid addiction (a public health crisis tied, at least to an extent, to loneliness, low incomes, and the atomization of society, according to numerous studies) may be contributing to thefts at its stores.

To be clear: Home Depot isn’t trying to claim that the opioid crisis alone is driving store thefts. Sometimes people just, well, steal things, whether the motivating factor be drugs, nice merchandise, or just cold hard cash.

Home Depot chief Craig Menear detailed that ambiguity—and the general trend across the industry—on Wednesday. “This is happening everywhere in retail,” he said. “We think this ties to the opioid crisis, but we’re not positive about that.”

This is a complicated issue, but just consider some of the major bullet points: Suicide rates have spiked 33% between 1999 and 2017, with the most outsized effects among 10-to-34-year olds and 35-to-54-year olds, according to the American Psychological Association (APA); earlier this year, the National Safety Council reported that, for the first time ever, opioid overdoses counted for more preventable deaths than automobile accidents. As in, well more than 100 people die from opioid overdose deaths every day.

We’ve been witnessing the public health effects of loneliness and poverty for a while now, whether it manifests itself as criminal activity, addiction, suicide, or all of the above. (And, by the way, there is significant evidence that all of these issues are related and constitute a vicious cycle.) The fact that a retailer the size of Home Depot is calling the issue is out is telling.

Read on for the day’s news.

Sy Mukherjee
sayak.mukherjee@fortune.com
@the_sy_guy

DIGITAL HEALTH

Sanofi's CEO wants to transform the company with a digitized boost—and an AI retrenchment. Sanofi CEO Paul Hudson (still fairly fresh on the job) is betting that technology such as artificial intelligence and robotics can save the drug maker billions of dollars in manufacturing costs. But there's a flip side to the story—as STAT News' Rebecca Robbins reports, the company is also retrenching from a collaboration with digital health firm Onudu (part of a joint venture with Alphabet's Verily). This isn't a full-on pullout—Sanofi will remain an investor, though no longer a top dog in the partnership. And it likely plays into the company's decision to step slowly away from its flagship cardiovascular and metabolic disease specialties. Still, it's an interesting pair of developments.

INDICATIONS

AstraZeneca-Daiichi partnership could pay dividends. British drug giant AstraZeneca's best on Japan's Daiichi Sankyo may pay major dividends in the cancer drug space. The companies' co-developed experimental treatment for metastatic breast cancer was able to prevent the deterioration of cancer for months in early-stage trials, the firms said. This has broader implications—especially because of the action mechanism ("antibody-drug conjugates" that aim to mitigate the effects of chemotherapy, among other uses) at the heart of the therapy. (Reuters)

THE BIG PICTURE

Insurers may win out in Supreme Court Obamacare case. The Supreme Court may hand a victory to health insurers in (yet another) case involving the Affordable Care Act (ACA). The issue at hand is whether or not insurers are owed certain reimbursements in order to cover the health costs of Americans with pre-existing conditions, who cannot be discriminated against under the ACA. And it's big money at stake—to the tune of $12 billion. (NPR)

REQUIRED READING

Analyst: Apple's Wearables Business Could Be Worth $100 Billion, by Don Reisinger

3 Lessons for Today's Economy from Paul Volcker's Career, by Erik Sherman

Why 90% of Investors in This New Silicon Valley Fund Are Women, by Michal Lev-Ram

Commentary: I Worked at McKinsey. Here's How the Firm Needs to Change, by Seth Green

Sign up for other Fortune newsletters.

About the Author
By Sy Mukherjee
See full bioRight Arrow Button Icon
Add Fortune on Google for similar content.

Latest in Newsletters

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Newsletters

How Home Depot is rebuilding retailing with AI
NewslettersCIO Intelligence
How Home Depot is rebuilding retailing with AI
By John KellJune 24, 2026
7 hours ago
As America turns 250, women’s financial independence remains a work in progress
NewslettersMPW Daily
As America turns 250, women’s financial independence remains a work in progress
By Emma HinchliffeJune 24, 2026
8 hours ago
As mega-funds grab 72% of all capital raised, the gap between VC’s haves and have-nots keeps widening
NewslettersTerm Sheet
As mega-funds grab 72% of all capital raised, the gap between VC’s haves and have-nots keeps widening
By Allie GarfinkleJune 24, 2026
14 hours ago
Business is moving past the tech bro era and learning to value ‘real people, real places’
NewslettersCEO Daily
Business is moving past the tech bro era and learning to value ‘real people, real places’
By Diane BradyJune 24, 2026
14 hours ago
Tencent COO and interactive entertainment group president Ren Yuxin on July 9, 2020 in Shanghai, China. (Photo: Wu Jun/VCG/Getty Images)
NewslettersFortune Tech
Tencent winds down its Japanese game studio investments
By Andrew NuscaJune 24, 2026
14 hours ago
Google DeepMind CEO Demis Hassabis (left) stands on a spiral staircase next to Google DeepMind researcher John Jumper.
NewslettersEye on AI
Defections from Google DeepMind prompt questions about Alphabet’s efforts to stay at the forefront of AI
By Jeremy KahnJune 23, 2026
1 day ago

Most Popular

The Pentagon said Iran War costs $29 billion, but the real cost is closer to $200 billion—and counting
Economy
The Pentagon said Iran War costs $29 billion, but the real cost is closer to $200 billion—and counting
By Jacqueline MunisJune 24, 2026
17 hours ago
After forcing workers back to the office, Goldman Sachs and JPMorgan Chase are now letting their staff work remotely—but only for the World Cup
Success
After forcing workers back to the office, Goldman Sachs and JPMorgan Chase are now letting their staff work remotely—but only for the World Cup
By Orianna Rosa RoyleJune 23, 2026
1 day ago
Amazon's record Prime Day masks a darker truth: Americans are spending more and getting less
Retail
Amazon's record Prime Day masks a darker truth: Americans are spending more and getting less
By Nick LichtenbergJune 24, 2026
9 hours ago
Ray Dalio just finished a 10-day trip to China. He says global leaders know America ‘doesn’t have what it takes to fight to maintain its empire’
Asia
Ray Dalio just finished a 10-day trip to China. He says global leaders know America ‘doesn’t have what it takes to fight to maintain its empire’
By Nick LichtenbergJune 24, 2026
10 hours ago
Now worth $200 million, Sarah Jessica Parker credits being ‘one of eight kids that struggled financially’ for her hunger, ambition, and work ethic
Success
Now worth $200 million, Sarah Jessica Parker credits being ‘one of eight kids that struggled financially’ for her hunger, ambition, and work ethic
By Orianna Rosa RoyleJune 24, 2026
17 hours ago
Current price of oil as of June 23, 2026
Personal Finance
Current price of oil as of June 23, 2026
By Joseph HostetlerJune 23, 2026
1 day ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.