• Home
  • Latest
  • Fortune 500
  • Finance
  • Tech
  • Leadership
  • Lifestyle
  • Rankings
  • Multimedia
Health

Tylenol Could Be Making You Less Empathetic

By
Michal Addady
Michal Addady
Down Arrow Button Icon
By
Michal Addady
Michal Addady
Down Arrow Button Icon
May 11, 2016, 3:57 PM ET
Research Shows Acetaminophen Relieves Not Just Pain, But Emotions As Well
CHICAGO, IL - APRIL 14: Tylenol tablets, which contain acetaminophen, are shown on April 14, 2015 in Chicago, Illinois. New research has shown that acetaminophen, which is found in many over-the-counter painkillers, can dull feelings of pleasure. Previous research found that the medication had a similar effect with feelings of dread. (Photo Illustration by Scott Olson/Getty Images)Photo by Scott Olson—Getty Images

Take Tylenol, and you might have a hard time feeling empathetic.

An Ohio State University study published in the scientific journal Social Cognitive and Affective Neuroscience found that acetaminophen, the painkilling ingredient in the Johnson & Johnson (JOHNSON-JOHNSON-40) brand medicine, not only suppresses your own pain, but causes you to perceive other people’s pain as being less severe.

The researchers conducted two experiments. The first asked 80 college students, half on acetaminophen and half on a placebo, to read scenarios and rate how they thought the character felt. The second experiment, which employed 114 students, had two parts. First, participants each experienced a noise blast and rated how unpleasant it was; they were then asked to rate how unpleasant they thought it would be for someone else. In the second part, they witnessed someone being socially rejected and rated how they thought they felt.

The participants who took acetaminophen consistently rated pain—both emotional and physical, and both their own and someone else’s—as less severe than those who took the placebo. This is particularly concerning considering a previous study conducted by Baldwin Way, the senior author of the Ohio State study showed the same ingredient also suppressed positive emotions. Researchers are unsure why acetaminophen has these effects.

Acetaminophen is the most common drug ingredient in the U.S. It’s found in more than 600 medicines, and nearly a quarter of American adults use it weekly. The Ohio State study authors have begun examining ibuprofen to see if it has similar effects.

Johnson & Johnson could not immediately be reached for comment.

About the Author
By Michal Addady
See full bioRight Arrow Button Icon

Latest in Health

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025

Most Popular

Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Finance
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam
By Fortune Editors
October 20, 2025
Fortune Secondary Logo
Rankings
  • 100 Best Companies
  • Fortune 500
  • Global 500
  • Fortune 500 Europe
  • Most Powerful Women
  • World's Most Admired Companies
  • See All Rankings
  • Lists Calendar
Sections
  • Finance
  • Fortune Crypto
  • Features
  • Leadership
  • Health
  • Commentary
  • Success
  • Retail
  • Mpw
  • Tech
  • Lifestyle
  • CEO Initiative
  • Asia
  • Politics
  • Conferences
  • Europe
  • Newsletters
  • Personal Finance
  • Environment
  • Magazine
  • Education
Customer Support
  • Frequently Asked Questions
  • Customer Service Portal
  • Privacy Policy
  • Terms Of Use
  • Single Issues For Purchase
  • International Print
Commercial Services
  • Advertising
  • Fortune Brand Studio
  • Fortune Analytics
  • Fortune Conferences
  • Business Development
  • Group Subscriptions
About Us
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • About Us
  • Press Center
  • Work At Fortune
  • Terms And Conditions
  • Site Map
  • Facebook icon
  • Twitter icon
  • LinkedIn icon
  • Instagram icon
  • Pinterest icon

Latest in Health

FDA Commissioner Dr. Marty Makary announced his resignation after a rocky year
PoliticsDonald Trump
FDA Commissioner Dr. Marty Makary announced his resignation after a rocky year
By The Associated Press and Matthew PerroneMay 12, 2026
16 hours ago
The Best Memorial Day Fitness Equipment Sales of 2026
HealthFitness
The Best Memorial Day Fitness Equipment Sales of 2026
By Christina SnyderMay 12, 2026
17 hours ago
The Best Memorial Day Treadmill Sales of 2026
HealthHealth Evergreen Fitness
The Best Memorial Day Treadmill Sales of 2026
By Christina SnyderMay 12, 2026
18 hours ago
Early Memorial Day Mattress sales of 2026: The Best Brands and Deals
Healthmattresses
Early Memorial Day Mattress sales of 2026: The Best Brands and Deals
By Christina SnyderMay 11, 2026
2 days ago
Poppi cofounder Allison Ellsworth
SuccessEntrepreneurs
Poppi cofounder maxed out credit cards and sold her car to fund the company—now, she’s a multimillionaire after a $1.95 billion sale
By Emma BurleighMay 11, 2026
2 days ago
American schools have been quietly killing recess to focus on test scores—and pediatricians are warning it’s a mistake
HealthEducation
American schools have been quietly killing recess to focus on test scores—and pediatricians are warning it’s a mistake
By Laura Ungar and The Associated PressMay 11, 2026
2 days ago

Most Popular

The Bezos family just donated $100 million to help achieve one of Mayor Zohran Mamdani’s top campaign promises
Politics
The Bezos family just donated $100 million to help achieve one of Mayor Zohran Mamdani’s top campaign promises
By Jake AngeloMay 12, 2026
14 hours ago
Forget U.S. debt, China's total borrowing is in 'a league of its own'—much worse and deteriorating faster, analyst says
Economy
Forget U.S. debt, China's total borrowing is in 'a league of its own'—much worse and deteriorating faster, analyst says
By Jason MaMay 11, 2026
2 days ago
Nearly 50,000 Lake Tahoe residents have to find a new power source after their energy source looks to redirect lines to data centers
Travel & Leisure
Nearly 50,000 Lake Tahoe residents have to find a new power source after their energy source looks to redirect lines to data centers
By Catherina GioinoMay 12, 2026
17 hours ago
U.S. hotels are calling the World Cup a 'non-event' and 80% warn bookings are falling short of expectations, report finds
North America
U.S. hotels are calling the World Cup a 'non-event' and 80% warn bookings are falling short of expectations, report finds
By Sasha RogelbergMay 12, 2026
1 day ago
Microsoft’s CFO admits she joined the tech giant without even knowing her salary—and then missed her first day of work
Success
Microsoft’s CFO admits she joined the tech giant without even knowing her salary—and then missed her first day of work
By Preston ForeMay 11, 2026
2 days ago
OpenAI CEO Sam Altman says Gen Z and millennials are using ChatGPT like a 'life advisor'—but college students might be one step ahead
Tech
OpenAI CEO Sam Altman says Gen Z and millennials are using ChatGPT like a 'life advisor'—but college students might be one step ahead
By Sydney LakeMay 10, 2026
3 days ago

© 2026 Fortune Media IP Limited. All Rights Reserved. Use of this site constitutes acceptance of our Terms of Use and Privacy Policy | CA Notice at Collection and Privacy Notice | Do Not Sell/Share My Personal Information
FORTUNE is a trademark of Fortune Media IP Limited, registered in the U.S. and other countries. FORTUNE may receive compensation for some links to products and services on this website. Offers may be subject to change without notice.