Nest Labs, a Palo Alto, Calif.-based maker of smart home devices like thermostats and smoke detectors, is raising upwards of $150 million in a new VC round that would value the company  north of $2 billion, according to Re/code. DST is expected to lead the round, with return backers including Google Ventures, Kleiner Perkins, Generation Investment Management, Lightspeed Venture Partners, Shasta Ventures and Venrock. www.nest.com

Didi Dache, a Chinese taxi-booking app, has raised $100 million in Series C funding from CITIC Capital ($60m) and existing investors like Tencent ($30m), according to a Chinese media report.www.xiaojukeji.com

Alexar Therapeutics Inc., a developer of liver x receptor agonists for both systemic and local use, has raised $21.5 million in Series A funding. The company was formed by NeXeption LLC, while the investment was co-led by New Science Ventures and Third Point Ventures. Palo Alto Investors also participated. www.alexartx.com

Agilis Biotherapeutics LLC, a New York-based synthetic biology-based company focused on rare genetic diseases, has raised $8 million in new VC funding. The company also announced a partnership with Intrexon Corp. (NYSE: XON), in order to develop a treatment for Friedreich’s ataxia.www.agilisbio.com

Floored, a New York-based provider of 3D data capture and visualization solutions for the real estate, architecture, interior design and furniture industries, has raised $5.26 million in Series A funding. RRE Ventures led the round, and was joined by Greycroft Partners and return backers Two Sigma Ventures, Lerer Ventures, and Felicis Ventures. www.floored.com

Retrofit, a Chicago-based provider of weight loss programs, has raised $5 million in Series B funding.Cambia Health Solutions led the round, and was joined by return backer DFJ. The company previously raised more than $8 million. www.retrofitme.com

Breaker, a producer and distributor of mobile video entertainment, has raised $2 million in seed funding. Japan’s Dream Incubator Inc. led the round, and was joined by Siemer Ventures. www.brkr.jp

AirVend, a Provo, Utah-based maker of cashless touchscreen devices for vending machines that will aid in nutrition disclosure regulations, has raised $1.2 million in seed funding. 365 Retail Markets led the round, and was joined by PS27 Ventures. www.air-vend.com

PRIVATE EQUITY DEALS

KIK Custom Products Inc., a portfolio company of CIC Capital Partners, has acquired the consumer business of Chemtura Corp. (NYSE: CHMT) for $300 million. www.kikcorp.com

New England Orthotic & Prosthetic Systems, a Branford, Conn.–based provider of orthotic and prosthetic patient care products and services, has raised an undisclosed amount of mezzanine funding from F.N.B. Capital Partners. New England Orthotic & Prosthetic Systems is a portfolio company ofSummer Street Capital Partners. www.neops.com

Peak Rock Capital has acquired Natural American Foods Inc., an Onsted, Mich.–based producer and distributor of honey and other food products. No financial terms were disclosed.www.naturalamericanfoods.com

Yumi’s Quality Foods, an Australian snack-maker, has raised an undisclosed amount of equity funding from Anacacia Capital. www.yumis.com.au

IPOs

Dicerna Pharmaceuticals, a Watertown, MA-based pharmaceutical company that develops RNA interference-based therapeutics, has filed for a $69 million IPO. It plans to trade on the Nasdaq under ticker symbol DRNA, with Jefferies, Leerink Swann and Stifel serving as lead underwriters. The company reports around a $10 million net loss on $7 million in revenue for 2013. Shareholders include Domain Associates (16.8% pre-IPO stake), Skyline Ventures (14.7%), Deerfield Management (13.4%), RA Capital (13.4%), Abingworth Management (10.3%), Brookside Capital (9.4%), S.R. One Ltd. (8%) and Oxford Bioscience Partners (7.3%). www.dicerna.com

Revance Therapeutics Inc., a Newark, Calif.-based developer of a platform technology that enables local, targeted delivery of large macromolecules across skin, has filed for an $86.25 million IPO. It plans to trade on the Nasdaq under ticker symbol RVNC, with Cowen & Co. and Piper Jaffray serving as lead underwriters. Shareholders include Essex Woodlands Health Ventures (36.2% pre-IPO stake), NovaQuest Capital (24.9%), Technology Partners (7.6%), Vivo Ventures (7%), Shepherd Ventures, Palo Alto Investors, Pac-Link Ventures and Essex Capital Corp. www.revance.com

OTHER DEALS

21st Century Fox (Nasdaq: FOXA) has agreed to sell its 47% stake in Star China TV to the channel’s majority owner, China Media Capital. No financial terms were disclosed. www.21cf.com

Fiat SpA has agreed to acquire the 41.46% stake in Chrysler that it does not already own, in a $4.35 billion deal.

Jonas Software, a unit of Constellation Software Inc. (TSX: CSU), has acquired Shortcuts Software Ltd., an Australia–based provider of business management solutions for the hair and beauty industry. No financial terms were disclosed. www.shortcutssoftware.com

Northern & Shell, a group owned by Richard Desmond, is considering a sale of British broadcast TV station Channel 5, according to the FT. Barclays is managing the process, which could garner around $1.2 billion.

PTC (Nasdaq: PTC) has acquired ThingWorx, an Exton, Penn.-based application development platform. The deal is valued at up to $130 million, including a $112 million up-front payment. ThingWorx backers included Safeguard Scientifics. www.thingworx.com

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